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It is our great pleasure to welcome you to Orlando to join us for our 17th annual conference! We hope you can join us this June 28-July 1, 2021 in Orlando, Florida at Hilton Bonnet Creek. This community of cardiac and vascular interventionalists has gathered yearly — first in Harrisburg, then Baltimore and now in Orlando. These experts in their field have passionately taught each other the latest techniques and innovations. They have leveraged these gatherings to impart pearls of knowledge and learn from one another. The C3 global summit has emphasized learning over status and scholarship over stature. It is the distinction of this level of collegiality that has, and will continue to, set C3 on its own path. The C3 Conference has been specifically designed for physicians who specialize in interventional cardiology, vascular surgery, and interventional radiology, as well as fellows, residents, and other healthcare professionals interested in atherosclerotic cardiovascular disease. Our mission remains to deliver educational innovation through a global exchange of scientific research, new techniques, and technologies to improve patient care and utilize best practices to improve lives of countless individuals across the world.